Health

Sleep Matters: What Apnea Studies Teach Us About Brain Health

Published

4 years ago

February 14, 2021

Do you ever wake up feeling tired? Have you been told that you snore? If so, you may have obstructive sleep apnea, one of the most common sleep disorders among adults. One of two major types of sleep apnea, obstructive apnea occurs when you stop breathing while asleep because something is blocking your airway, and it can be very dangerous to sufferers. And, interestingly, the impact of sleep apnea on health can be quite extensive. As recent studies of both obstructive and central sleep apnea demonstrate, the condition may be linked to memory problems and may even mimic Alzheimer’s disease’s impact on the brain.

Sleep Apnea: The Basics

We know that obstructive sleep apnea is very common among adults, but we don’t have particularly good data on the condition, with estimates ranging from 9-38%. However, we do know that men, older adults, and overweight individuals are more likely to suffer from this form of sleep apnea.

Central sleep apnea, a form of the condition characterized by the failure of the brain to trigger breathing during sleep, is more commonly linked to other health conditions, ranging from congestive heart failure to various neurological diseases, and may occur at any age. For example, children with Angelman syndrome are prone to both central and obstructive sleep apnea, as are young people with Prader-Willi syndrome.

Sleep And The Brain

Sleep is an important function of the brain, and our brain’s activity changes immensely while we sleep. When we don’t get enough sleep, or sleep poorly, though, the consequences extend far beyond simple fatigue. Given this, scientists studying the impact of sleep, or a lack thereof, on the brain have turned to obstructive sleep apnea patients as a sample group, and one thing they’ve discovered is that many people with obstructive sleep apnea demonstrate the same brain changes seen in Alzheimer’s patients, despite the fact that they were never diagnosed with any form of dementia.

Making Connections

Even before this study of sleep apnea patients, it was clear to researchers and doctors that Alzheimer’s and other forms of dementia were closely linked to sleep, and particularly to circadian rhythm disorders. As recent brain research has shown, Alzheimer’s patients often experience serious sleep disruption, which can cause them to get up and wander in the middle of the night and can complicate their care. Further research into the vulnerability of the primary circadian clock gene (Clk) to neurodegenerative disease is still underway.

Other Theories And Research Avenues

In addition to the research showing neurofibrillary tangles and beta-amyloid plaques in sleep apnea patients’ brains, ongoing work seeks to understand why these develop in this patient set. One working hypothesis suggests that insufficient deep sleep among obstructive sleep apnea patients may interfere with the body’s ability to clear beta-amyloid and other waste from the brain. Looking ahead, if researchers can determine why these patients develop plaques but do not develop dementia symptoms, this could offer valuable insights for the treatment of Alzheimer’s disease and related disorders.

Patients often dismiss sleep apnea as snoring or as a condition that just makes them feel a little tired, but the more we learn about it, the more concerning the long-term effects of this condition become. Just as researchers are taking the condition seriously as a topic of study, then, patients must take its management serious to mitigate its medical consequences.

Health

What Sets Why Not Natural Supplements Above Other Supplements Companies in the U.S.

Published

2 days ago

November 21, 2024

Michelle Langton

Photo courtesy of Why Not Natural

By: Georgette Virgo

In an industry plagued by minimal regulation and questionable practices, Why Not Natural Supplements sets a new standard in transparency and scientific excellence. Founded by chemical engineer Kelin Marquet, this female-owned supplement company challenges the status quo with clean and effective formulations backed by rigorous research.

Why Not Natural Supplements’ outlook on supplement creation contrasts starkly with many competitors in the $50 billion U.S. dietary supplement market. The Food and Drug Administration (FDA) does not require pre-market approval for supplements, which leaves consumers vulnerable to potentially ineffective or harmful products. Why Not Natural Supplements has implemented stringent self-imposed standards that go far beyond regulatory requirements.

“We’re on a mission to educate consumers about what a supplement should look like,” says Kelin Marquet. “As a mother of three, I’m motivated by creating supplements that I feel comfortable giving to my own family.”

A Science-First Approach to Supplement Formulation

Why Not Natural Supplements’ commitment to scientific integrity begins with its founder. Marquet’s background in chemical engineering informs every aspect of the company’s product development process.

“I use my background and strong understanding of science to pore through research articles and choose active ingredients that work – not cheap substitutes you usually find in supplements,” Kelin Marquet explains.

This science-first perspective extends to the company’s use of bioavailable forms of nutrients and its emphasis on third-party testing. Why Not Natural Supplements rigorously tests every product—including their best-selling Organic Vitamin D3 Liquid Drops with K2, 4-in-1 Magnesium Complex, Liquid Vitamin A (10,000 IU) with Coconut MCT Oil, and many others—for purity and potency. This practice sets the company apart in an industry where such thorough quality control is far from standard.

Transparency and Clean Formulations

Why Not Natural Supplements’ transparency is evident in its viewpoint on ingredient selection and labeling. The company maintains a list of ingredients that will never appear in its products, including artificial preservatives, colors, flavors, and common allergens.

“It’s not just about what’s in a supplement – it’s essential what’s not in it, too,” Marquet emphasizes. This philosophy extends to the company’s use of clean, minimalist formulations that avoid unnecessary fillers and additives.

The company provides consumers with clear, accurate information about each product’s contents. This level of transparency is rare in an industry where, according to the National Institutes of Health, supplement labels may not always accurately reflect the product’s contents.

Kelin Marquet emphasizes that each product formulation undergoes rigorous scientific scrutiny, with every ingredient serving a specific, research-backed purpose. “We don’t just throw ingredients together because they’re trendy,” Marquet explains. “Every component in our formulas is there for a reason, in its most bioavailable form, and at the optimal dosage.”

Education and Consumer Empowerment

Why Not Natural Supplements’ mission extends beyond creating high-quality supplements to educating consumers about supplement quality and safety. The company uses its social media platforms and website to provide in-depth information about ingredient sourcing, manufacturing processes, and the science behind its formulations.

This educational outlook is particularly crucial in light of the rapid growth of e-commerce in the supplement industry. As online sales platforms capture an increasing market share, the traditional role of natural and specialty retailers as information gatekeepers is diminishing. Why Not Natural Supplements is stepping into this gap, providing consumers with the knowledge they need to understand dietary supplements and find one that best fits their needs.

“We’re not just selling supplements,” Marquet states. “We’re empowering consumers to make informed decisions about their health by showing them exactly what goes into each formula and why.”

In an industry where regulation is minimal and quality can be inconsistent, Why Not Natural Supplements stands out as a company committed to raising the bar through its science-based method, commitment to transparency, and focus on consumer education.

“Our goal is to change how individuals see natural supplements,” Marquet concludes. “We believe that by prioritizing quality, efficacy, and transparency, we can help consumers reclaim their health and trust in their supplements.”