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40 and Pregnant: How IVF has Helped Women have Children Later in Life

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As recent reports of a 62 year-old Spanish woman successfully giving birth after IVF treatment began to circulate, following similar reports of 72 year-old Daljinder Kaur giving birth earlier in 2021, prospective parents around the world have a new ray of hope in starting a family.

There is growing consensus spanning medical disciplines that advanced assisted reproductive techniques are able to effectively help women facing infertility or adverse social conditions overcome the obstacles to becoming mothers.

IVF has been a boon in helping couples provide infertility solutions, helping them reproduce. However, the success of a couple at pregnancy calls for the inputs of a healthcare scientist, an embryologist in particular, who plays an imperative role in the entire process.  

Providing diagnostic services and embryological procedures, a reproductive embryologist performs careful examination of quality embryos to help couples have the best chance at becoming parents.

Embryo quality is one of the most important factors based on which a women’s pregnancy is defined. Embryo quality correlates with the maternal age, causes of infertility, ovarian stimulation parameters or embryo cohort size, and the outcome of the IVF cycle invariably depends on the above factors.

“As every woman is different, so the quality, gene expression and development of the embryo vary. However, as you age, the embryo quality is bound to deteriorate which increases the chances of infertility of aneuploidy, stating the abnormality of the embryos,” stated Dr. Goral Gandhi, an embryologist who is also a community advocate and educator of IVF and ART in India.

So how can older mothers, who want to opt for IVF or maybe conceive on their own make sure that their embryos are as healthy as possible? The answer lies in embryo testing, as it helps mitigate the chances of an unhealthy pregnancy, ensuring that the fetus is devoid of chromosomal abnormalities before implantation, suggests Dr Goral Gandhi. Her work in research and evaluation of pre-implantation genetic screening technology, and fertility-treatment-assisted pregnancies makes Gandhi an established authority.

“Older women understand their time is limited. If they lose three months because of a miscarriage, that’s a lot of time. Most patients like the idea of having as much information in front of them as possible, so they don’t have to go through the very difficult waiting period between the embryo transfer and the pregnancy test if the embryo wouldn’t have resulted in pregnancy,” says Goldman, an assistant professor of obstetrics and gynecology in reproductive endocrinology and infertility at Northwestern University Feinberg School of Medicine.

When it comes to women above 30, it is deemed appropriate to transfer multiple embryos, to boost the overall success of the procedure. The choice is, however, elective and can be best if decided upon the consideration of the embryologist. “Numbers for live birth rates show that older DNA can be rescued by modern IVF, and this offers great hope to women in their 40s who hope to be a mum,” Queensland Fertility Group medical director Dr David Molloy told The Sunday Mail.

Although ART has been used to treat infertility in both men, women of all age brackets, it calls for an extensive evaluation of treatment options by both the patient and the doctor before opting for any procedure.

Your age shouldn’t be a bar to measure your success and ability as a parent, and IVF has helped women exceed their fertility limits, and give birth to healthy babies regardless of their age.

Michelle has been a part of the journey ever since Bigtime Daily started. As a strong learner and passionate writer, she contributes her editing skills for the news agency. She also jots down intellectual pieces from categories such as science and health.

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Health

Finding Your Best Fit: Are GLP-1 Medications Right for Your Weight Loss Journey?

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Over the past few years, a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists has been gaining attention, not only for treating type 2 diabetes but also in the field of weight management.

With obesity affecting “at least one in five adults (20%) in each U.S. state,” according to the CDC, many individuals are seeking effective solutions that can complement diet and exercise. Two of the most discussed options are GLP-1 injections for weight loss and GLP-1/GIP for weight loss, both of which have shown promising results. 

However, deciding if these medications are right for you isn’t a one-size-fits-all process; it’s essential to determine if GLP-1s are right for you to get you to be your best self in 2025. SimpleFixRx — a healthcare service dedicated to personalized options — can help you explore GLP-1s therapy as part of your 2025 broader health plan. 

Understanding GLP-1 receptor agonists

GLP-1 receptor agonists were initially designed to help regulate blood sugar in individuals with type 2 diabetes by mimicking a hormone that controls insulin secretion, slows digestion, and reduces appetite. The recent spotlight on GLP-1 injectors for weight loss and GLP-1/ GIP for weight loss stems from studies showing that these medications can help many people achieve significant, sustained weight loss — often in the 10-15 percent range or more of their body weight — when paired with healthier eating habits and increased physical activity. 

Key benefits:

  • Enhanced blood sugar control: For individuals with type 2 diabetes, these medications can significantly lower hemoglobin A1C levels. 
  • Appetite regulation: By slowing gastric emptying and impacting appetite signals, GLP-1s can help reduce unhealthy food cravings.
  • Possible cardiovascular benefits: Some research suggests that certain GLP-1s may offer heart-protective effects, reducing the risk of cardiac events.

Who can benefit from GLP-1?

GLP-1 receptor agonists have emerged as a promising option for individuals facing various metabolic and weight-related challenges. Whether you’re dealing with type 2 diabetes or seeking a meaningful way to jump-start weight loss, therapies like GLP-1/ GIP for weight loss and GLP-1 injections for weight loss could help bridge the gap where traditional diet and exercise might fall short.

Individuals with type 2 diabetes

GLP-1s remain a staple in controlling high blood sugar for patients who’ve struggled with traditional oral medications or lifestyle measures alone. If you have type 2 diabetes, speak with your healthcare provider to see if adding a GLP-1 might improve your overall management plan.

Those with obesity or weight-related health concerns

If your body mass index (BMI) is 30 or above — or you’re overweight (BMI 25–29.9) and have additional complications like prediabetes, hypertension, or high cholesterol — GLP-1s might be a strong consideration. The appetite-suppressing effects often help jump-start weight loss.

People seeking a catalyst for lifestyle changes

Even if you haven’t succeeded with traditional diets or exercise routines, medications such as GLP-1/ GIP for weight loss or GLP-1 injections for weight loss may help you regain momentum. Still, a commitment to long-term lifestyle improvements — such as more balanced eating and regular physical activity — is vital to achieving the best results.

Patients with hard-to-control metabolic factors

Some people face genetic or metabolic hurdles that make weight management exceptionally challenging. GLP-1s can help bridge that gap, providing extra support where willpower and standard lifestyle interventions might not suffice on their own.

By combining medical guidance, like that from the experts of SimpleFixRx, with regular follow-ups and a commitment to healthier habits, eligible patients may find these therapies to be a game-changer in achieving sustainable weight management and better overall health.

GLP Squared

Some compound pharmacies are now combining options for GLP medications, allowing for the microdosing of a combination of GLP and GLP1/GIP.  Microdosing has numerous benefits for patients, including reduced nausea, a more steady release of medication, and decreased inflammation, among others. SimpleFix does offer GLP squared, and it is less expensive than GLP1/ GIP alone.

The SimpleFixRx approach

SimpleFixRx specializes in providing personalized healthcare solutions, including access to GLP-1 therapies, through a convenient, patient-centered platform. Their team of licensed healthcare providers works closely with patients to:

  • Assess eligibility: SimpleFixRx professionals review each patient’s medical history, lifestyle habits, and specific health goals to determine if GLP-1 therapy is appropriate.
  • Offer comprehensive care plans: Beyond prescribing medications, SimpleFixRx aims to create a holistic approach that includes nutritional guidance and exercise plans, ensuring GLP-1 therapy is supported by healthier daily habits.
  • Monitor progress: Through regular follow-up appointments, patients can collaborate with the SimpleFixRx team to fine-tune their regimen and address any side effects or emerging concerns.

Potential side effects and considerations

While GLP-1s offer noteworthy benefits, they aren’t free of potential drawbacks. The most frequently reported side effects include nausea, diarrhea, and, in some cases, vomiting — especially when first beginning treatment — but these often ease as your body adjusts. Other, more serious risks include pancreatitis or gallbladder issues, though these are generally less common.

Your medical history and personal goals should guide any decision to start GLP-1 therapy. Certain gastrointestinal or thyroid conditions, for instance, could make these medications less suitable. Women who are or might become pregnant also need specialized guidance, as safety data for pregnancy remains limited.

Making the decision with SimpleFixRx

Dr. Garrett H. Garner, M.D., F.A.C.O.G., a board-certified OB/GYN with over two decades of experience in North Texas, highlights the importance of individualized care. “We take the time to review each patient’s medical history, dietary habits, and long-term health objectives. Medications like GLP-1/ GIP or GLP-1 can be game-changers — but they work best within a broader strategy that includes nutrition, exercise, and regular follow-up.”

Before you opt for any GLP-1 medication, consider asking your healthcare provider or a service like SimpleFixRx these five questions:

  1. “Am I a good candidate for GLP-1s based on my health profile?”
  2. “How will this therapy interact with other treatments or conditions I have?”
  3. “What lifestyle changes, if any, should I implement to maximize the benefits?”
  4. “Which medication — GLP-1/ GIP vs. GLP-1 — would best suit my needs?”
  5. “How often should I schedule follow-up appointments to assess progress and adjust my treatment plan?”

By partnering with a dedicated healthcare service like SimpleFixRx, you can gain access to expert guidance, personalized care plans, and ongoing support — all crucial components to long-term success.

These therapies are tools, not magic solutions, as sustainable progress often hinges on a combination of effective medication, mindful eating, regular physical activity, and consistent medical oversight. However, with the proper support structure and commitment, GLP-1 medications can be a transformative part of your journey toward better health.

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